作者
Cinzia Crivellaro, Mauro Signorelli, Luca Guerra, Elena De Ponti, Alessandro Buda, Carlotta Dolci, Cecilia Pirovano, Sergio Todde, Robert Fruscio, Cristina Messa
发表日期
2012/10/1
期刊
Gynecologic oncology
卷号
127
期号
1
页码范围
131-135
出版商
Academic Press
简介
OBJECTIVES
To evaluate the role of the metabolic characteristics of cervical tumor uptake as predictors of a) lymph node (LN) metastases, b) recurrence, in the preoperative staging of early-stage cervical cancer.
METHODS
89 patients with FIGO stage IB1 and IIA <4cm cervical cancer were imaged with FDG-PET/CT before radical hysterectomy and pelvic lymphadenectomy. PET/CT images were analyzed and correlated to histological findings. Maximum and mean standardized uptake value (SUVmax, SUVmean), metabolic tumor volume (MTV), total lesion glycolysis (TLG) of cervical lesions were calculated by an iterative adaptive algorithm. These parameters were correlated to the presence of: a) LN metastases, b) relapse after primary treatment.
RESULTS
Out of the 89 patients who underwent preoperative PET/CT scan for staging purpose, 16 were negative at cervical level: they were all pN0 and without …
学术搜索中的文章
C Crivellaro, M Signorelli, L Guerra, E De Ponti, A Buda… - Gynecologic oncology, 2012