作者
Alaa Alashi, Tamanna Khullar, Amgad Mentias, A Marc Gillinov, Eric E Roselli, Lars G Svensson, Zoran B Popovic, Brian P Griffin, Milind Y Desai
发表日期
2020/1/1
期刊
Cardiovascular Imaging
卷号
13
期号
1_Part_1
页码范围
12-21
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to determine whether baseline left ventricular global longitudinal strain (LV-GLS) and changes in left ventricular ejection fraction (LVEF) in a subgroup of subjects at post-operative follow-up added prognostic value in patients undergoing aortic valve (AV) surgery.
Background
In patients with chronic severe aortic regurgitation (AR) and preserved LVEF, sensitive markers are needed to decide timing of AV surgery.
Methods
This was an observational study in 865 patients (asymptomatic/mildly symptomatic, 52 ± 15 years of age, 79% men) with ≥3+ chronic AR and preserved LVEF of ≥50% who underwent AV surgery between 2003 and 2015. All patients had baseline echocardiography (and LV-GLS imaging), whereas 285 patients underwent post-operative echocardiography (including LV-GLS). Primary outcome was mortality.
Results
Only 478 patients (56%) patients had …
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A Alashi, T Khullar, A Mentias, AM Gillinov, EE Roselli… - Cardiovascular Imaging, 2020