作者
Amgad Mentias, Pejman Raeisi-Giglou, Nicholas G Smedira, Ke Feng, Kimi Sato, Oussama Wazni, Mohamad Kanj, Scott D Flamm, Maran Thamilarasan, Zoran B Popovic, Harry M Lever, Milind Y Desai
发表日期
2018/8/21
期刊
Journal of the American College of Cardiology
卷号
72
期号
8
页码范围
857-870
出版商
American College of Cardiology Foundation
简介
Background
A high proportion of patients with hypertrophic cardiomyopathy (HCM) have evidence of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR).
Objectives
This study sought to assess the incremental prognostic utility of LGE in patients with HCM.
Methods
We studied 1,423 consecutive low-/intermediate-risk patients with HCM (age ≥18 years) with preserved left ventricular (LV) ejection fraction (mean age 66 ± 14 years, 60% men) who underwent transthoracic echocardiography (TTE) (including dimensions and LV outflow tract gradients) and CMR (including LGE as a % of LV mass) at our center between January 2008 and December 2015. The primary composite endpoint was sudden cardiac death (SCD) and appropriate implantable cardioverter-defibrillator discharge. The percent 5-year SCD risk score was calculated.
Results
The mean 5-year SCD risk score was 2.3 ± 2.0 …
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A Mentias, P Raeisi-Giglou, NG Smedira, K Feng… - Journal of the American College of Cardiology, 2018