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Parent-based sexual health interventions have received considerable attention as one factor that can increase safer sexual behavior among youth; however, to our knowledge, the evidence linking parent-based interventions to youth sexual behaviors has not been empirically synthesized.

To examine the association of parent-based sexual health interventions with 3 primary youth outcomes—delayed sexual activity, condom use, and parent-child sexual communication—as well as several secondary outcomes. We also explored potential moderators of intervention effectiveness.

A systematic search was conducted of studies published through March 2018 using MEDLINE, PsycINFO, Communication Source, and CINAHL databases and relevant review articles.

Studies were included if they: (1) sampled adolescents (mean age, ≤18 years), (2) included parents in a …