作者
Wi-Sun Ryu, Sung-Ho Woo, Dawid Schellingerhout, Min Uk Jang, Kyoung-Jong Park, Keun-Sik Hong, Sang-Wuk Jeong, Jeong-Yong Na, Ki-Hyun Cho, Joon-Tae Kim, Beom Joon Kim, Moon-Ku Han, Jun Lee, Jae-Kwan Cha, Dae-Hyun Kim, Soo Joo Lee, Youngchai Ko, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Jong-Moo Park, Kyusik Kang, Kyung Bok Lee, Tai Hwan Park, Juneyoung Lee, Heung-Kook Choi, Kiwon Lee, Hee-Joon Bae, Dong-Eog Kim
发表日期
2017/1/1
期刊
Brain
卷号
140
期号
1
页码范围
158-170
出版商
Oxford University Press
简介
Leukoaraiosis or white matter hyperintensities are frequently observed on magnetic resonance imaging of stroke patients. We investigated how white matter hyperintensity volumes affect stroke outcomes, generally and by subtype. In total, 5035 acute ischaemic stroke patients were enrolled. Strokes were classified as large artery atherosclerosis, small vessel occlusion, or cardioembolism. White matter hyperintensity volumes were stratified into quintiles. Mean age (± standard deviation) was 66.3 ± 12.8, 59.6% male. Median (interquartile range) modified Rankin Scale score was 2 (1–3) at discharge and 1 (0–3) at 3 months; 16.5% experienced early neurological deterioration, and 3.3% recurrent stroke. The Cochran-Mantel-Haenszel test with adjustment for age, stroke severity, sex, and thrombolysis status showed that the distributions of 3-month modified Rankin Scale scores differed across white matter …
学术搜索中的文章
WS Ryu, SH Woo, D Schellingerhout, MU Jang… - Brain, 2017