查看文章

2398 2003 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim DOI: 10.1002/ange. 200250745 Angew. Chem. 2003, 115, 2398–2402 unless the thread is very short. Here we describe photoand thermally responsive shuttles (1–3) in which the macrocycle moves over a relatively large distance (approximately 1.5 nm) between two discrete stations with remarkable positional integrity (even at room temperature), despite the fact that the discrimination between the binding sites is caused only by “matched” and “mismatched” hydrogen-bonding motifs. Each translational form is stable until a new stimulus is applied. The basis for the new shuttles lies in the photochemical and thermal interconversion of fumaramide and maleamide groups.[12] The trans-olefin bisamide acts as an excellent template for the formation of benzylic amide macrocycle-based rotaxanes (for example, E-4; Figure 2) because the amide carbonyl …