作者
Michele Marchioni, Marco Bandini, Felix Preisser, Zhe Tian, Anil Kapoor, Luca Cindolo, Giulia Primiceri, Francesco Berardinelli, Alberto Briganti, Shahrokh F Shariat, Luigi Schips, Pierre I Karakiewicz
发表日期
2019/5/1
期刊
European urology focus
卷号
5
期号
3
页码范围
488-496
出版商
Elsevier
简介
Background
The benefit of cytoreductive nephrectomy (CNT) for cancer-specific mortality (CSM)-free survival is unclear in contemporary metastatic non-clear cell renal cell carcinoma (non-ccmRCC) patients.
Objective
To assess the role of CNT in non-ccmRCC patients.
Design, setting, and participants
Within Surveillance, Epidemiology, and End Results registry (2001–2014), we identified patients with non-ccmRCC.
Intervention
CNT versus no CNT in non-ccmRCC patients.
Outcome measurements and statistical analysis
Multivariable logistic regression, cumulative incidence, competing-risks regression models, incremental survival benefit (ISB), conditional survival, and landmark analyses were performed. Sensitivity analyses focused on histological subtypes and most contemporary patients (2010–2014).
Results and limitations
Of 851 patients with non-ccmRCC, 67.6% underwent CNT. In multivariable logistic …
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