作者
Augusto Lopes Souto, Josean Fechine Tavares, Marcelo Sobral Da Silva, Margareth de Fátima Formiga Melo Diniz, Petrônio Filgueiras de Athayde-Filho, José Maria Barbosa Filho
发表日期
2011/10/11
来源
Molecules
卷号
16
期号
10
页码范围
8515-8534
出版商
MDPI
简介
Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010. The assays were conducted mostly in vivo, and carrageenan-induced pedal edema was the most used experimental model. Of the 49 alkaloids evaluated, 40 demonstrated anti-inflammatory activity. Of these the most studied type were the isoquinolines. This review was based on NAPRALERT data bank, Web of Science and Chemical Abstracts. In this review, 95 references are cited.
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