作者
Amita Gupta, Uma Nayak, Malathi Ram, Ramesh Bhosale, Sandesh Patil, Anita Basavraj, Arjun Kakrani, Sheeja Philip, Dipali Desai, Jayagowri Sastry, Robert C Bollinger, Byramjee Jeejeebhoy Medical College–Johns Hopkins University Study Group
发表日期
2007/7/15
期刊
Clinical Infectious Diseases
卷号
45
期号
2
页码范围
241-249
出版商
The University of Chicago Press
简介
Background . In contrast with many other countries, isoniazid preventative therapy is not recommended in clinical care guidelines for human immunodeficiency virus (HIV)—infected persons with latent tuberculosis (TB) in India.
Methods . Seven hundred fifteen HIV-infected mothers and their infants were prospectively followed up for 1 year after delivery at a public hospital in Pune, India. Women were evaluated for active TB during regular clinic visits, and tuberculin skin tests were performed. World Health Organization definitions for confirmed, probable, and presumed TB were used. Poisson regression was performed to determine correlates of incident TB, and adjusted probabilities of mortality were calculated.
Results . Twenty-four of 715 HIV-infected women who were followed up for 480 postpartum person-years developed TB, yielding a TB …
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