作者
Stephanie K Nishi, Nancy Babio, Indira Paz-Graniel, Lluís Serra-Majem, Jesús Vioque, Montserrat Fitó, Dolores Corella, Xavier Pintó, Aurora Bueno-Cavanillas, Josep A Tur, Laura Diez-Ricote, J Alfredo Martinez, Carlos Gómez-Martínez, Andrés González-Botella, Olga Castañer, Andrea Alvarez-Sala, Cristina Montesdeoca-Mendoza, Marta Fanlo-Maresma, Naomi Cano-Ibáñez, Cristina Bouzas, Lidia Daimiel, María Ángeles Zulet, John L Sievenpiper, Kelly L Rodriguez, Zenaida Vázquez-Ruiz, Jordi Salas-Salvadó
发表日期
2023/3/8
期刊
BMC medicine
卷号
21
期号
1
页码范围
82
出版商
BioMed Central
简介
Background
Water intake and hydration status have been suggested to impact cognition; however, longitudinal evidence is limited and often inconsistent. This study aimed to longitudinally assess the association between hydration status and water intake based on current recommendations, with changes in cognition in an older Spanish population at high cardiovascular disease risk.
Methods
A prospective analysis was conducted of a cohort of 1957 adults (aged 55–75) with overweight/obesity (BMI between ≥ 27 and < 40 kg/m2) and metabolic syndrome from the PREDIMED-Plus study. Participants had completed bloodwork and validated, semiquantitative beverage and food frequency questionnaires at baseline, as well as an extensive neuropsychological battery of 8 validated tests at baseline and 2 years of follow-up. Hydration status was determined by serum osmolarity calculation and categorized as < 295 …
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SK Nishi, N Babio, I Paz-Graniel, L Serra-Majem… - BMC medicine, 2023