作者
Md Ali Milon, Md Abdul Muhit, Durajan Goshwami, Mohammad Mehedi Masud, Bilkis Begum
发表日期
2012/7/1
期刊
International Journal of Pharmaceutical Sciences and Research
卷号
3
期号
7
页码范围
2233
出版商
International Journal of Pharmaceutical Sciences and Research
简介
The present study was undertaken to evaluate antioxidant, cytotoxic and antimicrobial activity of Sonneratia alba bark. The carbon tetrachloride, chloroform soluble partitionate of methanolic extract and crude methanolic extract showed significant antioxidant property using 1, 1-diphenyl-2-pecrylhydrazyl (DPPH) scavenging assay, of which chloroform partitionate and crude extract demonstrated highest activity with IC50 value of 12µg/ml and 14µg/ml respectively. In the brine shrimp lethality bioassay, LC50 values obtained from the best fit line slope were 0.812, 14.94, 0.831 and 3.288 µg/ml for standard (Vincristine sulphate), n-Hexane, carbon tetrachloride and chloroform soluble partitionate of methanolic extract respectively. The carbon tetrachloride soluble fraction revealed moderate activities against
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MA Milon, MA Muhit, D Goshwami, MM Masud… - International Journal of Pharmaceutical Sciences and …, 2012