作者
Thomas Müller, Alois Philipp, Andreas Luchner, Christian Karagiannidis, Thomas Bein, Michael Hilker, Leopold Rupprecht, Julia Langgartner, Markus Zimmermann, Matthias Arlt, Jan Wenger, Christof Schmid, Günter AJ Riegger, Michael Pfeifer, Matthias Lubnow
发表日期
2009/12
期刊
Critical Care
卷号
13
页码范围
1-10
出版商
BioMed Central
简介
Introduction
Mortality of severe acute respiratory distress syndrome in adults is still unacceptably high. Extracorporeal membrane oxygenation (ECMO) could represent an important treatment option, if complications were reduced by new technical developments.
Methods
Efficiency, side effects and outcome of treatment with a new miniaturized device for veno-venous extracorporeal gas transfer were analysed in 60 consecutive patients with life-threatening respiratory failure.
Results
A rapid increase of partial pressure of arterial oxygen/fraction of inspired oxygen (PaO2/FiO2) from 64 (48 to 86) mmHg to 120 (84 to 171) mmHg and a decrease of PaCO2 from 63 (50 to 80) mmHg to 33 (29 to 39) mmHg were observed after start of the extracorporeal support (P < 0.001). Gas exchange capacity of the device averaged 155 …
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T Müller, A Philipp, A Luchner, C Karagiannidis, T Bein… - Critical Care, 2009