作者
Giorgio L Colombo, Daria Bettoni, Sergio Di Matteo, Camilla Grumi, Cinzia Molon, Daniela Spinelli, Gaetano Mauro, Alessia Tarozzo, Giacomo M Bruno
发表日期
2014/9/10
来源
Vascular health and risk management
页码范围
569-576
出版商
Taylor & Francis
简介
Background
TachoSil® is a medicated sponge coated with human fibrinogen and human thrombin. It is indicated as a support treatment in adult surgery to improve hemostasis, promote tissue sealing, and support sutures when standard surgical techniques are insufficient. This review systematically analyses the international scientific literature relating to the use of TachoSil in hemostasis and as a surgical sealant, from the point of view of its economic impact.
Methods
We carried out a systematic review of the PubMed literature up to November 2013. Based on the selection criteria, papers were grouped according to the following outcomes: reduction of time to hemostasis; decrease in length of hospital stay; and decrease in postoperative complications.
Results
Twenty-four scientific papers were screened, 13 (54%) of which were randomized controlled trials and included a total of 2,116 patients, 1,055 of whom were …
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GL Colombo, D Bettoni, S Di Matteo, C Grumi, C Molon… - Vascular health and risk management, 2014