作者
Richard M Lovering, Joseph A Roche, Robert J Bloch, Patrick G De Deyne
发表日期
2007/5/1
期刊
Archives of physical medicine and rehabilitation
卷号
88
期号
5
页码范围
617-625
出版商
WB Saunders
简介
Lovering RM, Roche JA, Bloch RJ, De Deyne PG. Recovery of function in skeletal muscle following 2 different contraction-induced injuries.
OBJECTIVE
To determine if the proliferation of myogenic cells is equally important to recovery of contractile function after 2 different types of contraction-induced muscle injuries.
DESIGN
Randomized trial.
SETTING
Muscle biology laboratory.
ANIMALS
Adult male Sprague-Dawley rats.
INTERVENTIONS
Tibialis anterior muscles were injured by a single lengthening contraction with large strain (1R) or multiple lengthening contractions with small strain (MR). The hindlimbs of some animals in each group were irradiated before injury to prevent proliferation of myogenic cells during recovery.
MAIN OUTCOME MEASURES
Contractile tension was measured immediately after injury and 3, 7, 14, and 21 days after injury. Permeation to Evans blue dye was used to assay membrane …
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RM Lovering, JA Roche, RJ Bloch, PG De Deyne - Archives of physical medicine and rehabilitation, 2007