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Results: Massive embolism (66.2% vs. 36.6%, p< 0.001) and in-hospital mortality (21.1%, 1.4%, p< 0.001) were higher in the high NLR group. In multivariate regression analysis NLR≥ 5.7, systolic blood pressure (BP)< 90 mm Hg, serum glucose> 126 mg/dl, heart rate> 110 beats/min, and PCO2< 35 or> 50 mm Hg were predictors of in-hospital mortality. The optimal NLR cutoff value was 5.7 for mortality in receiver operating characteristic (ROC) analysis. Having an NLR value above 5.7 was found to be associated with a 10.8 times higher mortality rate than an NLR value below 5.7.

Conclusions: In patients presenting with APE, NLR value is an independent predictor of in-hospital mortality and may be used for clinical risk classification.