作者
Sunyoung Lee, Tae Wook Kang, Kyoung Doo Song, Min Woo Lee, Hyunchul Rhim, Hyo Keun Lim, So Yeon Kim, Dong Hyun Sinn, Jong Man Kim, Kyunga Kim, Sang Yun Ha
发表日期
2021/3/1
期刊
Annals of surgery
卷号
273
期号
3
页码范围
564-571
出版商
LWW
简介
Objective:
We compared surgical resection (SR) and radiofrequency ablation (RFA) as first-line treatment in patients with hepatocellular carcinoma (HCC) based on the risk of microvascular invasion (MVI).
Background:
The best curative treatment modality between SR and RFA in patients with HCC with MVI remains unclear.
Methods:
Data from 2 academic cancer center-based cohorts of patients with a single, small (≤ 3 cm) HCC who underwent SR were used to derive (n= 276) and validate (n= 101) prediction models for MVI using clinical and imaging variables. The MVI prediction model was developed using multivariable logistic regression analysis and externally validated. Early recurrence (< 2 years) based on risk stratification between SR (n= 276) and RFA (n= 240) was evaluated via propensity score matching.
Results:
In the multivariable analysis, alpha-fetoprotein (≥ 15 ng/mL), protein induced by vitamin K …
学术搜索中的文章
S Lee, TW Kang, KD Song, MW Lee, H Rhim, HK Lim… - Annals of surgery, 2021