作者
Hongmei Zeng, Kexin Sun, Maomao Cao, Rongshou Zheng, Xibin Sun, Shuzheng Liu, Zhiyi Zhang, Yuqin Liu, Guizhou Guo, Guohui Song, Yigong Zhu, Xianghong Wu, Bingbing Song, Xianzhen Liao, Yanfang Chen, Mingyang Song, Edward Giovannucci, Guihua Zhuang, Wenqiang Wei, Wanqing Chen, Jie He
发表日期
2020/12
期刊
BMC gastroenterology
卷号
20
页码范围
1-12
出版商
BioMed Central
简介
Background
We initiated the first multi-center cluster randomized trial of endoscopic screening for esophageal cancer and gastric cancer in China. The objective of the study was to report the baseline screening findings in this trial.
Methods
We recruited a total of 345 eligible clusters from seven screening centers. In the intervention group, participants from high-risk areas were screened by endoscopy; in non-high-risk areas, high-risk individuals were identified using a questionnaire and advised for endoscopy. Lugol’s iodine staining in esophagus and indigo carmine dye in stomach were performed to aid in the diagnosis of suspicious lesions. The primary outcomes of this study were the detection rate (proportion of positive cases among individuals who underwent endoscopic screening) and early detection rate (the proportion of positive cases with stage 0/I among all positive cases).
Results
A total of 149,956 …
学术搜索中的文章
H Zeng, K Sun, M Cao, R Zheng, X Sun, S Liu, Z Zhang… - BMC gastroenterology, 2020