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Malaria remains one of the world’s most prevalent tropical diseases because of its high mortality and morbidity burden, as well as its economic and social impacts on the development of malaria-endemic countries. The emergence and spread of chloroquine-resistant Plasmodium falciparum, the causative agent of the most lethal form of human malaria, are major obstacles in the control of the disease. 1, 2 More recently, concern has been raised as to whether there is evidence of resistance to artemisinins, which could endanger the artemisinin combination therapies (ACTs) now widely adopted. Although continued attempts to develop a vaccine for malaria are ongoing, drugs continue to be the only treatment option,. 3, 4 The most currently used antimalarials are potent blood schizontocidals; ie, they act rapidly against the parasite forms that invade erythrocytes and cause the well-described malaria symptoms. 2 …