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DATABASES The EMBL nucleotide sequence database The Nucleotide Sequence Database (1) is the main activity of the group. This work is done in collaboration with GenBank®, USA (2) and the DNA Database of Japan (DDBJ). Each of the three groups collects a portion of the total reported sequence data and exchanges it with the others on a daily basis. The explosive growth of the database continues and the latest release (Release 34; March 1993) reports just under 130 million bases from 105,340 entries. The database approximately doubles in size every 18 months. Improved data handling methods and compulsory data submission policies on the part of most of the major molecular biology journals make it possible to deal with the increasing volumes of sequence data that are being generated. Close collaboration with genome project databases has resulted in refined procedures for automatic inclusion of …