作者
A Trinh, P Wong, MC Fahey, J Brown, A Churchyard, BJ Strauss, PR Ebeling, PJ Fuller, F Milat
发表日期
2016/3/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
101
期号
3
页码范围
1190-1197
出版商
Oxford University Press
简介
Context
Cerebral palsy (CP) increases fracture risk through diminished ambulation, nutritional deficiencies, and anticonvulsant medication use. Studies examining bone mineral density (BMD) in adults with CP are limited.
Objective
To examine the relationship between body composition, BMD, and fractures in adults with CP. The effect of functional, nutritional, and endocrine factors on BMD and body composition is also explored.
Design
Retrospective cross-sectional study.
Setting and Participants
Forty-five adults with CP (mean age, 28.3 ± 11.0 years) who had dual-energy x-ray absorptiometry imaging at a single tertiary hospital between 2005 and 2015.
Results
Seventeen (38%) had a past history of fragility fracture; 43% had a Z-score of ≤ −2.0 at the lumbar spine (LS) and 41% at the femoral neck (FN). In …
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