作者
Ioannis D Papadimitriou, Alejandro Lucia, Yannis P Pitsiladis, Vladimir P Pushkarev, Dmitry A Dyatlov, Evgeniy F Orekhov, Guilherme G Artioli, João Paulo LF Guilherme, Antonio H Lancha, Valentina Ginevičienė, Pawel Cieszczyk, Agnieszka Maciejewska-Karlowska, Marek Sawczuk, Carlos A Muniesa, Anastasia Kouvatsi, Myosotis Massidda, Carla Maria Calò, Fleur Garton, Peter J Houweling, Guan Wang, Krista Austin, Anastasiya M Druzhevskaya, Irina V Astratenkova, Ildus I Ahmetov, David J Bishop, Kathryn N North, Nir Eynon
发表日期
2016/12
期刊
BMC genomics
卷号
17
页码范围
1-8
出版商
BioMed Central
简介
Background
To date, studies investigating the association between ACTN3 R577X and ACE I/D gene variants and elite sprint/power performance have been limited by small cohorts from mixed sport disciplines, without quantitative measures of performance. Aim: To examine the association between these variants and sprint time in elite athletes.
Methods
We collected a total of 555 best personal 100-, 200-, and 400-m times of 346 elite sprinters in a large cohort of elite Caucasian or African origin sprinters from 10 different countries. Sprinters were genotyped for ACTN3 R577X and ACE ID variants.
Results
On average, male Caucasian sprinters with the ACTN3 577RR or the ACE DD genotype had faster best 200-m sprint time than their 577XX (21.19 ± 0.53 s vs. 21.86 ± 0.54 s, p = 0.016) and ACE II (21.33 ± 0.56 …
学术搜索中的文章
ACTN3 R577X and ACE I/D gene variants influence performance in elite sprinters: a multi-cohort study
ID Papadimitriou, A Lucia, YP Pitsiladis, VP Pushkarev… - BMC genomics, 2016