作者
William A Florez, Ezequiel García-Ballestas, Fernando Maeda, Andrei Joaquim, Orlin Pavlov, Luis Rafael Moscote-Salazar, Asterios Tsimpas, Rafael Martinez-Perez
发表日期
2021/1/1
来源
Clinical neurology and neurosurgery
卷号
200
页码范围
106320
出版商
Elsevier
简介
Background
Aspirin has been associated with a decreasing risk of subarachnoid hemorrhage due to its anti-inflammatory mechanism of action and potential protective properties against aneurysm growth.
Objective
To determine the association between aneurysmal subarachnoid hemorrhage and aspirin use.
Methods
A systematic review of the literature and a meta-analysis were performed across the PubMed database. The following keywords were used: “aspirin, acetylsalicylic acid, 2-acetyloxy-benzoic acid, ruptured intracranial aneurysm, aneurysmal subarachnoid hemorrhage, spontaneous subarachnoid hemorrhage, intracerebral hemorrhage, spontaneous aneurysmal hemorrhage, spontaneous intracerebral bleeding”. Studies that were performed with animals or analyzed patients with traumatic brain injury were excluded. A total of five studies were included in our meta-analysis, with a total of 19,222 patients …
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WA Florez, E García-Ballestas, F Maeda, A Joaquim… - Clinical neurology and neurosurgery, 2021