作者
Crisanto Diez-Quevedo, Josep Lupón, Beatriz González, Agustín Urrutia, Lucía Cano, Roser Cabanes, Salvador Altimir, Ramon Coll, Teresa Pascual, Marta De Antonio, Antoni Bayes-Genis
发表日期
2013/8/20
期刊
International Journal of Cardiology
卷号
167
期号
4
页码范围
1217-1225
出版商
Elsevier
简介
Background
This study was designed to assess whether depression and the use of antidepressants were related to long-term mortality in heart failure.
Methods
Heart failure outpatients (n = 1017) from a specialized tertiary unit in Spain were prospectively studied for a median follow-up of 5.4 years (IQR 3.1–8.1). Depressive symptoms were assessed using an abbreviated version of the geriatric depression scale. Survival rates during the study period (August 2001 until December 2010) and hazard ratios (HR) for mortality were adjusted by several demographic and clinical variables.
Results
Depressive symptoms were detected in 302 patients (29.7%) at baseline and 222 (21.8%) de novo during follow-up; 304 patients (29.9%) received at least one prescription of antidepressants, mainly selective serotonin reuptake inhibitors (92.8%); 441 patients (43.4%) died. In a multivariate Cox proportional hazard model …
学术搜索中的文章
C Diez-Quevedo, J Lupón, B González, A Urrutia… - International Journal of Cardiology, 2013