作者
Masoud Etemadifar, Nahad Sedaghat, Ali Aghababaee, Parisa K Kargaran, Mohammad Reza Maracy, Mazdak Ganjalikhani-Hakemi, Milad Rayani, Amir Parsa Abhari, Reza Khorvash, Mehri Salari, Hosein Nouri
发表日期
2021/6/1
期刊
Multiple Sclerosis and Related Disorders
卷号
51
页码范围
102915
出版商
Elsevier
简介
Background
COVID-19 is speculated to increase the likelihood of relapsing-remitting multiple sclerosis (RRMS) exacerbation.
Objective
To investigate the association between contraction of COVID-19 and incidence of acute MS attacks in RRMS patients six months post-infection.
Methods
This retrospective cohort study compares the risk of relapse in RRMS patients with (n=56) and without COVID-19 (n=69). Incidence of relapse was recorded for six-month following contraction of COVID-19. Incidence of RRMS exacerbation in patients with COVID-19 was compared to patients without COVID-19 (the independent control group) and the same patients six months prior to the COVID-19 pandemic.
Results
A lower incidence rate of RRMS exacerbation was observed in patients that contracted COVID-19 than in patients who did not contract COVID-19 (incidence rate ratio: 0.275; p=0.026). Self-controlled analysis showed no …
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M Etemadifar, N Sedaghat, A Aghababaee… - Multiple Sclerosis and Related Disorders, 2021