作者
M Adibrad, P Deyhimi, M Ganjalikhani Hakemi, P Behfarnia, M Shahabuei, L Rafiee
发表日期
2012/8
期刊
Journal of periodontal research
卷号
47
期号
4
页码范围
525-531
出版商
Blackwell Publishing Ltd
简介
Adibrad M, Deyhimi P, Ganjalikhani Hakemi M, Behfarnia P, Shahabuei M, Rafiee L. Signs of the presence of Th17 cells in chronic periodontal disease. J Periodont Res 2012; 47: 525–531. © 2012 John Wiley & Sons A/S
Background and Objective: The aim of this study was to identify the specific markers of T helper 17 (Th17) cells and their variations in people suffering from chronic periodontal disease in comparison with normal control subjects.
Material and Methods: In 30 patients with periodontitis and 30 normal control subjects, the mRNA expressions of interleukin (IL)‐17A and retinoic orphan receptor C2 (RORC2) were measured by quantitative RT‐PCR. The protein levels of IL‐17A and RORC2 were also evaluated by immunohistochemistry. The levels of these markers were compared between healthy and diseased periodontal tissues by the Mann–Whitney U‐test.
Results: In periodontal lesions, IL …
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