作者
Kim A Eagle, Eva Kline-Rogers, Shaun G Goodman, Enrique P Gurfinkel, Alvaro Avezum, Marcus D Flather, Christopher B Granger, Steve Erickson, Kami White, Philippe Gabriel Steg
发表日期
2004/7/15
期刊
The American journal of medicine
卷号
117
期号
2
页码范围
73-81
出版商
Elsevier
简介
PURPOSE
To determine the rates of patient adherence to key evidence-based therapies at 6 months after hospital discharge for an acute coronary syndrome.
METHODS
In this nonrandomized, prospective, multinational, multicenter study, adherence to aspirin, beta-blockers, statins, or angiotensin-converting enzyme (ACE) inhibitors 6 months after discharge for myocardial infarction or unstable angina was assessed in 21,408 patients aged 18 years or older. Patients were enrolled at 104 tertiary and community hospitals representing a broad range of care facilities and practice settings (e.g., teaching vs. nonteaching).
RESULTS
Of 13,830 patients, discontinuation of therapy was observed at 6-month follow-up in 8% of those taking aspirin on discharge, 12% of those taking beta-blockers, 20% of those taking ACE inhibitors, and 13% of those taking statins. In a multivariate analysis, adherence to beta-blocker therapy …
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KA Eagle, E Kline-Rogers, SG Goodman, EP Gurfinkel… - The American journal of medicine, 2004