作者
Iqbal Ike K Ahmed, Antonio Fea, Leon Au, Robert E Ang, Paul Harasymowycz, Henry D Jampel, Thomas W Samuelson, David F Chang, Douglas J Rhee, COMPARE Investigators
发表日期
2020/1/1
期刊
Ophthalmology
卷号
127
期号
1
页码范围
52-61
出版商
Elsevier
简介
Purpose
To compare the efficacy of different microinvasive glaucoma surgery (MIGS) devices for reducing intraocular pressure (IOP) and medications in open-angle glaucoma (OAG).
Design
Prospective, multicenter, randomized clinical trial.
Participants
One hundred fifty-two eyes from 152 patients aged 45 to 84 years with OAG, Shaffer angle grade III–IV, best-corrected visual acuity (BCVA) 20/30 or better, and IOP 23 to 39 mmHg after washout of all hypotensive medications. Eyes with secondary glaucoma other than pseudoexfoliative or pigmentary glaucoma, angle closure, previous incisional glaucoma surgery, or any significant ocular pathology other than glaucoma were excluded.
Intervention
Study eyes were randomized 1:1 to standalone MIGS consisting of either 1 Hydrus Microstent (Ivantis, Inc, Irvine, CA) or 2 iStent Trabecular Micro Bypass devices (Glaukos Inc, San Clemente, CA). Follow-up was performed 1 …
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IIK Ahmed, A Fea, L Au, RE Ang, P Harasymowycz… - Ophthalmology, 2020