作者
Marjori Matzke, Tatsuo Kanno, Bruno Huettel, Lucia Daxinger, Antonius JM Matzke
发表日期
2007/10/1
来源
Current opinion in plant biology
卷号
10
期号
5
页码范围
512-519
出版商
Elsevier Current Trends
简介
RNA-directed DNA methylation contributes substantially to epigenetic regulation of the plant genome. Methylation is guided to homologous DNA target sequences by 24nt ‘heterochromatic’ small RNAs produced by nucleolar-localized components of the RNAi machinery and a plant-specific RNA polymerase, Pol IV. Plants contain unusually large and diverse populations of small RNAs, many of which originate from transposons and repeats. These sequences are frequent targets of methylation, and they are able to bring plant genes in their vicinity under small RNA-mediated control. RNA-directed DNA methylation can be removed by enzymatic demethylation, providing plants with a versatile system that facilitates epigenetic plasticity. In addition to subduing transposons, RNA-directed DNA methylation has roles in plant development and, perhaps, stress responses.
引用总数
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M Matzke, T Kanno, B Huettel, L Daxinger, AJM Matzke - Current opinion in plant biology, 2007