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A photokilling approach for pathogenic bacteria is demonstrated using a new type of magnetic nanoprobe as the photokilling agent. In addition to their magnetic property, the nanoprobes have other features including a photocatalytic property and the capacity to target bacteria. The nanoprobes comprise iron oxide/titania (Fe₃O₄@TiO₂) core/shell magnetic nanoparticles. As dopamine molecules can self‐assemble onto the surface of the titania substrate, dopamine is used as the linker to immobilize succinic anhydride onto the surfaces of the Fe₃O₄@TiO₂ nanoparticles. This is followed by the immobilization of IgG via amide bonding. We demonstrate that the IgGFe₃O₄@TiO₂ magnetic nanoparticles not only have the capacity to target several pathogenic bacteria, but they also can effectively inhibit the cell growth of the bacteria targeted by the nanoparticles under irradiation of a low‐power UV lamp within a short …