作者
Alan D Kaye, George M Jeha, Vanessa Moll, Ceressa T Ward, Matthew R Watson, John Thomas Wynn, Maxwell A Hockstein, Kevin M Hall, Omar Viswanath, Ivan Urits, Amit Prabhakar, Elyse M Cornett
发表日期
2020/9
来源
Advances in therapy
卷号
37
页码范围
3707-3722
出版商
Springer Healthcare
简介
Introduction
Platelet diseases and dysfunction are taught early in medical school to all future physicians. Understanding of the coagulation cascade and hemostatic mechanisms has allowed for targeted pharmacological therapies that have been significantly impactful in clinical practice. Platelets are an early participant in hemostasis physiologically and under pathophysiological states.
Methods
A review of literature involving platelet disfunction.
Results
Various presentations of platelet diseases and dysfunction challenge clinicians and require a firm understanding of normal platelet function, drugs that mediate or modulate platelet effectiveness, and nonpharmacologic etiologies of platelet diseases and dysfunction with corresponding best practice treatment approaches.
Conclusion
This review summarizes normal and abnormal states associated with platelets and treatment strategies.
学术搜索中的文章
AD Kaye, GM Jeha, V Moll, CT Ward, MR Watson… - Advances in therapy, 2020