作者
Joy John Mammen, Snehil Kumar, Lovely Thomas, Gunjan Kumar, Anand Zachariah, Lakshmanan Jeyaseelan, John Victor Peter, Anup Agarwal, Aparna Mukherjee, Pranab Chatterjee, Tarun Bhatnagar, Jess Elizabeth Rasalam, Binila Chacko, Thenmozhi Mani, Melvin Joy, Priscilla Rupali, Malathi Murugesan, Dolly Daniel, B Latha, Sunita Bundas, Vivek Kumar, Ravi Dosi, Janakkumar R Khambholja, Rosemarie de Souza, B Thrilok Chander, Shalini Bahadur, Simmi Dube, Amit Suri, Aikaj Jindal, Om Shrivastav, Vijay Barge, Archana Bajpayee, Pankaj Malhotra, Neha Singh, Muralidhar Tambe, Nimisha Sharma, Shreepad Bhat, Ram S Kaulgud, Anil Gurtoo, D Himanshu Reddy, Kamlesh Upadhyay, Ashish Jain, Tinkal C Patel, Irfan Nagori, Pramod R Jha, KV Sreedhar Babu, C Aparna, Sunil Jodharam Panjwani, M Natarajan, Milind Baldi, Vrushali Khirid Khadke, Seema Dua, Ravindraa Singh, Ashish Sharma, Jayashree Sharma, Yojana A Gokhale, Pragya D Yadav, Gajanan Sapkal, Himanshu Kaushal, V Saravana Kumar
发表日期
2021/10/1
期刊
BMJ open
卷号
11
期号
10
页码范围
e050571
出版商
British Medical Journal Publishing Group
简介
Objective
Large data on the clinical characteristics and outcome of COVID-19 in the Indian population are scarce. We analysed the factors associated with mortality in a cohort of moderately and severely ill patients with COVID-19 enrolled in a randomised trial on convalescent plasma.
Design
Secondary analysis of data from a Phase II, Open Label, Randomized Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated Complications in Moderate Disease.
Setting
39 public and private hospitals across India during the study period from 22 April to 14 July 2020.
Participants
Of the 464 patients recruited, two were lost to follow-up, nine withdrew consent and two patients did not receive the intervention after randomisation. The cohort of 451 participants with known outcome at 28 days was analysed.
Primary outcome measure
Factors associated with all-cause mortality at 28 days …
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JJ Mammen, S Kumar, L Thomas, G Kumar… - BMJ open, 2021