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Tumour development is greatly influenced by the systemic inflammatory response. Inflammatory factors, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphcyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), mirror the balance between systemic inflammation and anti-tumour response. The current investigation examined the predictive and prognostic value of NLR, PLR, and LMR in advanced gastric cancer (GC) patients.

This study is a retrospective, observational analysis involving 105 GC patients treated with neoadjuvant chemotherapy (NAC). The study population included patients who met the eligibility criteria. The relationship between NLR, PLR, LMR and demographic and clinical variables was assessed using the Χ² test. Survival data were analysed by Kaplan-Meier curves.

High NLR levels were associated with more advanced tumour stage. Higher risk of no …