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There are limited data describing the presenting characteristics, management, and outcomes of diabetic and nondiabetic patients with an acute coronary syndrome (ACS).

To examine differences in these factors, patients with ST-segment elevation acute myocardial infarction, non–ST-segment elevation acute myocardial infarction, and unstable angina were enrolled in a large multinational coronary disease registry.

The Global Registry of Acute Coronary Events is a prospective observational study of patients hospitalized with an ACS at 94 hospitals in 14 countries. The study sample consisted of 5403 patients with ST-segment elevation acute myocardial infarction, 4725 with non–ST-segment elevation acute myocardial infarction, and 5988 with unstable angina.

Approximately 1 in 4 patients presented to participating hospitals with a history of diabetes. Patients with diabetes were …