作者
Vera Graute, Nathalie Jansen, Christopher Übleis, Michael Seitz, Markus Hartenbach, Michael Karl Scherr, Sven Thieme, Paul Cumming, Katharina Klanke, Reinhold Tiling, Peter Bartenstein, Marcus Hacker
发表日期
2012/2
期刊
European journal of nuclear medicine and molecular imaging
卷号
39
页码范围
271-282
出版商
Springer-Verlag
简介
Purpose
The aim of the present study was to identify prostate-specific antigen (PSA) threshold levels, as well as PSA velocity, progression rate and doubling time in relation to the detectability and localization of recurrent lesions with [18F]fluorocholine (FC) PET/CT in patients after radical prostatectomy.
Methods
The study group comprised 82 consecutive patients with biochemical relapse after radical prostatectomy. PSA levels measured at the time of imaging were correlated with the FC PET/CT detection rates in the entire group with PSA velocity (in 48 patients), with PSA doubling time (in 47 patients) and with PSA progression (in 29 patients).
Results
FC PET/CT detected recurrent lesions in 51 of the 82 patients (62%). The median PSA value was significantly higher in PET-positive than in PET-negative patients (4.3 ng …
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