作者
Selin Kara, Dominik Spickermann, Joerg H Schrittwieser, Christian Leggewie, Willem JH van Berkel, Isabel WCE Arends, Frank Hollmann
发表日期
2013
期刊
Green chemistry
卷号
15
期号
2
页码范围
330-335
出版商
Royal Society of Chemistry
简介
1,4-Butanediol is shown to be an efficient cosubstrate to promote NAD(P)H-dependent redox biocatalysis. The thermodynamically and kinetically inert lactone coproduct makes the regeneration reaction irreversible. Thereby not only the molar surplus of cosubstrate is dramatically reduced but also faster reaction rates are obtained.
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S Kara, D Spickermann, JH Schrittwieser, C Leggewie… - Green chemistry, 2013