作者
Young Seok Kim, Jong Hoon Kim, Sang Min Yoon, Eun Kyung Choi, Seung Do Ahn, Sang-wook Lee, Jin Cheon Kim, Chang Sik Yu, Hee Chul Kim, Tae Won Kim, Heung Moon Chang
发表日期
2009/7/1
期刊
International Journal of Radiation Oncology* Biology* Physics
卷号
74
期号
3
页码范围
796-802
出版商
Elsevier
简介
PURPOSE
To investigate the prognostic impact of lymph node ratio (LNR) on survival in the patients with Stage III rectal cancer.
METHODS AND MATERIALS
We retrospectively reviewed the data of 421 consecutive patients who underwent total mesorectal excision followed by chemoradiotherapy for rectal cancer from 1996 to 2006. The 232 patients with positive lymph nodes (LNs) were divided into four groups according to LNR quartiles: LNR ≤0.1 (n = 69), ≤0.2 (n = 49), ≤0.4 (n = 54), and >0.4 (n = 60). The association between LNR and survival was evaluated by the Kaplan-Meier method and multivariate analysis with covariates of prognostic significance in univariate analysis.
RESULTS
The median numbers of examined and positive LNs were 17 and 3, respectively, and the median LNR was 0.20 (range, 0.03–1). There was a strong correlation between the number of positive LNs and LNR (r = 0.724, p < 0 …
学术搜索中的文章
YS Kim, JH Kim, SM Yoon, EK Choi, S Do Ahn, S Lee… - International Journal of Radiation Oncology* Biology …, 2009