作者
Kuo-Chuan Hung, Ming Yew, Yao-Tsung Lin, Jen-Yin Chen, Li-Kai Wang, Ying-Jen Chang, Yang-Pei Chang, Kuo-Mao Lan, Chun-Ning Ho, Cheuk-Kwan Sun
发表日期
2022/4/1
来源
British journal of anaesthesia
卷号
128
期号
4
页码范围
644-654
出版商
Elsevier
简介
Background
The efficacy of i.v. or topical lidocaine as an anaesthesia adjunct in improving clinical outcomes in patients receiving gastrointestinal endoscopic procedures under propofol sedation remains unclear.
Methods
Electronic databases (MEDLINE, EMBASE, and Cochrane Library) were searched for RCTs comparing the clinical outcomes with or without lidocaine application (i.v. or topical) in patients receiving propofol for gastrointestinal endoscopic procedures from inception to 29 March 2021. The primary outcome was propofol dosage, while secondary outcomes included procedure time, recovery time, adverse events (e.g. oxygen desaturation), post-procedural pain, and levels of endoscopist and patient satisfaction.
Results
Twelve trials (1707 patients) published between 2011 and 2020 demonstrated that addition of i.v. (n=7) or topical (n=5) lidocaine to propofol sedation decreased the level of post …
学术搜索中的文章
KC Hung, M Yew, YT Lin, JY Chen, LK Wang… - British journal of anaesthesia, 2022