作者
Marc W Deyell, Kyoung-Min Park, Yuchi Han, David S Frankel, Sanjay Dixit, Joshua M Cooper, Mathew D Hutchinson, David Lin, Fermin Garcia, Rupa Bala, Michael P Riley, Edward Gerstenfeld, David J Callans, Francis E Marchlinski
发表日期
2012/9/1
期刊
Heart rhythm
卷号
9
期号
9
页码范围
1465-1472
出版商
Elsevier
简介
BACKGROUND
Frequent ventricular premature depolarizations (VPDs) can cause reversible left ventricular (LV) dysfunction. However, not all patients normalize their LV function after VPD elimination.
OBJECTIVE
To evaluate predictors of recovery of LV function following the elimination of frequent VPDs.
METHODS
We identified patients with ≥10% VPDs/24 h and an LV ejection fraction of <50% who underwent successful ablation between 2007 and 2011. Subjects were classified as having reversible (≥10% increase to a final LV ejection fraction of ≥50%) or irreversible (≤10% increase or final LV ejection fraction <50%) LV dysfunction on the basis of echocardiographic follow-up. A reference group with ≥10% VPDs but normal LV function was identified.
RESULTS
One hundred fourteen patients with ≥10% VPDs were identified; 66 had preserved and 48 had impaired LV function. Over a median follow-up of …
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