作者
Siobhan F Clarke, Eileen F Murphy, Orla O'Sullivan, Alice J Lucey, Margaret Humphreys, Aileen Hogan, Paula Hayes, Maeve O'Reilly, Ian B Jeffery, Ruth Wood-Martin, David M Kerins, Eamonn Quigley, R Paul Ross, Paul W O'Toole, Michael G Molloy, Eanna Falvey, Fergus Shanahan, Paul D Cotter
发表日期
2014/12/1
期刊
Gut
卷号
63
期号
12
页码范围
1913-1920
出版商
BMJ Publishing Group
简介
Objective
The commensal microbiota, host immunity and metabolism participate in a signalling network, with diet influencing each component of this triad. In addition to diet, many elements of a modern lifestyle influence the gut microbiota but the degree to which exercise affects this population is unclear. Therefore, we explored exercise and diet for their impact on the gut microbiota.
Design
Since extremes of exercise often accompany extremes of diet, we addressed the issue by studying professional athletes from an international rugby union squad. Two groups were included to control for physical size, age and gender. Compositional analysis of the microbiota was explored by 16S rRNA amplicon sequencing. Each participant completed a detailed food frequency questionnaire.
Results
As expected, athletes and controls differed significantly with respect to plasma creatine kinase (a marker of extreme exercise), and …
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SF Clarke, EF Murphy, O O'Sullivan, AJ Lucey… - Gut, 2014
