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In The Lancet Public Health, Joshua D Bundy and colleagues report on how social determinants of health (SDoH) affect the association between race and premature mortality in a large cohort of adults in the USA. 1 By linking data from the US National Health and Nutrition Examination Survey from 1999 to 2018 to data from the National Death Index, the authors explored the associations between premature mortality (defined as death before 75 years of age) and SDoH across eight categories: employment status, family income-to-poverty ratio, food security, education level, health-care access, health insurance status, and being married or living with a partner. An increasing burden of SDoH was associated with higher risk of premature death. Additionally, after adjusting for age, gender, and number of unfavourable SDoH, no increased risk of mortality was observed among Black adults compared with White adults …