作者
Maria Vitoria Oliveira Dantas, Paula Lima Nogueira, Filipe de Oliveira Lima, Denis Candeia Pereira Oliveira, Emanuelly Nara Severiano Gomes, José Filipe Bacalhau Rodrigues, Solomon Kweku Sagoe Amoah, Rosana Araújo Rosendo, Elizandra Silva da Penha, Antonio Flávio Medeiros Dantas, Marcus Vinícius Lia Fook, Rogério Lacerda-Santos, Luanna Abílio Diniz Melquiades de Medeiros
发表日期
2021/10
期刊
European Journal of Dentistry
卷号
15
期号
04
页码范围
741-745
出版商
Thieme Medical and Scientific Publishers Pvt. Ltd.
简介
Objective The objective of this study was to evaluate the hemostatic activity of the sap from Jatropha mollissima (Pohl) Baill. in rats.
Materials and Methods Twenty-four Wistar rats were randomized into four groups (n = 6): the JM25 and JM40 groups were treated with ethanolic extract from the sap of J. mollissima, in a concentration of 25 and 40 mg·mL1, respectively; the MO group was treated with Monsel’s solution and the control group SC with a 0.9% sodium chloride solution.
Statistical Analysis Data were submitted to the Kurskal–Wallis’ test, followed by Dunn’s post hoc (p < 0.05).
Results There was a significant reduction in the bleeding time of the group from the JM25 extract (p = 0.001) when compared with MO and SC. There were no statistically significant differences between groups JM25 and JM40 (p > 0.05). The JM25 group did not present rebleeding, a result significantly different from the MO group (p …
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