作者
Robert D Meade, Naoto Fujii, Lacy M Alexander, Gabrielle Paull, Jeffrey C Louie, Andreas D Flouris, Glen P Kenny
发表日期
2015/9/1
期刊
The Journal of physiology
卷号
593
期号
17
页码范围
4055-4065
简介
Key points
- Recent work demonstrates that nitric oxide (NO) contributes to cutaneous vasodilatation during moderate (400 W of metabolic heat production) but not high (700 W of metabolic heat production) intensity exercise bouts performed in the heat (35°C).
- The present study evaluated whether the impairment in NO‐dependent cutaneous vasodilatation was the result of a greater accumulation of reactive oxygen species during high (700 W of metabolic heat production) relative to moderate (500 W of metabolic heat production) intensity exercise.
- It was shown that local infusion of ascorbate (an anti‐oxidant) improves NO‐dependent forearm cutaneous vasodilatation during high intensity exercise in the heat.
- These findings provide novel insight into the physiological mechanisms governing cutaneous blood flow during exercise‐induced heat stress and provide direction for future research exploring whether …
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RD Meade, N Fujii, LM Alexander, G Paull, JC Louie… - The Journal of physiology, 2015