作者
M Schlumberger, A Hitzel, ME Toubert, C Corone, F Troalen, MH Schlageter, F Claustrat, S Koscielny, D Taieb, M Toubeau, F Bonichon, F Borson-Chazot, L Leenhardt, C Schvartz, C Dejax, I Brenot-Rossi, M Torlontano, F Tenenbaum, S Bardet, F Bussiere, JJ Girard, O Morel, O Schneegans, JL Schlienger, A Prost, D So, F Archambeaud, M Ricard, E Benhamou
发表日期
2007/7/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
92
期号
7
页码范围
2487-2495
出版商
Oxford University Press
简介
Background: Serum thyroglobulin (Tg) is the marker of differentiated thyroid cancer after initial treatment and TSH stimulation increases its sensitivity for the diagnosis of recurrent disease.
Aim: The goal of the study is to compare the diagnostic values of seven methods for serum Tg measurement for detecting recurrent disease both during L-T4 treatment and after TSH stimulation.
Methods: Thyroid cancer patients who had no evidence of persistent disease after initial treatment (total thyroidectomy and radioiodine ablation) were studied at 3 months on L-T4 treatment (Tg1) and then at 9–12 months after withdrawal or recombinant human TSH stimulation (Tg2). Sera with anti-Tg antibodies or with an abnormal recovery test result were excluded from Tg analysis with the corresponding assay. The results of serum Tg determination were compared to the clinical status of the patient at the …
引用总数
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M Schlumberger, A Hitzel, ME Toubert, C Corone… - The Journal of Clinical Endocrinology & Metabolism, 2007