作者
Liong Liem, Marc Russo, Frank JPM Huygen, Jean-Pierre Van Buyten, Iris Smet, Paul Verrills, Michael Cousins, Charles Brooker, Robert Levy, Timothy Deer, Jeffery Kramer
发表日期
2013/9/1
期刊
Neuromodulation: Technology at the Neural Interface
卷号
16
期号
5
页码范围
471-482
出版商
Elsevier
简介
Objectives
This multicenter prospective trial was conducted to evaluate the clinical performance of a new neurostimulation system designed to treat chronic pain through the electrical neuromodulation of the dorsal root ganglia (DRG) neurophysiologically associated with painful regions of the limbs and/or trunk.
Materials and Methods
Thirty-two subjects were implanted with a novel neuromodulation device. Pain ratings during stimulation were followed up to six months and compared with baseline ratings. Subjects also completed two separate reversal periods in which stimulation was briefly stopped in order to establish the effects of the intervention.
Results
At all assessments, more than half of subjects reported pain relief of 50% or better. At six months postimplant, average overall pain ratings were 58% lower than baseline (p < 0.001), and the proportions of subjects experiencing 50% or more reduction in pain …
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L Liem, M Russo, FJPM Huygen, JP Van Buyten, I Smet… - Neuromodulation: Technology at the Neural Interface, 2013