作者
Marie-Elisabeth Bougnoux, Guillaume Kac, Philippe Aegerter, Christophe d’Enfert, Jean-Yves Fagon, CandiRea Study Group
发表日期
2008/2
期刊
Intensive care medicine
卷号
34
页码范围
292-299
出版商
Springer-Verlag
简介
Objective
To determine the concomitant incidence, molecular diversity, management and outcome of nosocomial candidemia and candiduria in intensive care unit (ICU) patients in France.
Design
A 1-year prospective observational study in 24 adult ICUs.
Patients
Two hundred and sixty-two patients with nosocomial candidemia and/or candiduria.
Measurements and results
Blood and urine samples were collected when signs of sepsis were present. Antifungal susceptibility of Candida strains was determined; in addition, all blood and 72% of urine C. albicans isolates were analyzed by using multi-locus sequence type (MLST). The mean incidences of candidemia and candiduria were 6.7 and 27.4/1000 admissions, respectively. Eight percent of candiduric patients developed candidemia …
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ME Bougnoux, G Kac, P Aegerter, C d'Enfert, JY Fagon… - Intensive care medicine, 2008