作者
D Hammoudi, C Ayoub Moubareck, Noha Hakime, M Houmani, A Barakat, Z Najjar, M Suleiman, N Fayad, R Sarraf, D Karam Sarkis
发表日期
2015/7/1
期刊
International Journal of Infectious Diseases
卷号
36
页码范围
56-61
出版商
Elsevier
简介
Objectives
The acquisition of carbapenemases by Acinetobacter baumannii is reported increasingly worldwide, but data from Lebanon are limited. The aims of this study were to evaluate the prevalence of imipenem-resistant A. baumannii in Lebanon, identify resistance determinants, and detect clonal relatedness.
Methods
Imipenem-resistant A. baumannii were collected from nine Lebanese hospitals during 2012. Antimicrobial susceptibility, the cloxacillin effect, and ethylenediaminetetraacetic acid (EDTA) synergy were determined. Genes encoding carbapenemases and insertion sequence ISAba1 were screened via PCR sequencing. ISAba1 position relative to genes encoding Acinetobacter-derived cephalosporinases (ADCs) and OXA-23 was studied by PCR mapping. Clonal linkage was examined by enterobacterial repetitive intergenic consensus PCR (ERIC-PCR).
Results
Out of 724 A. baumannii isolated in …
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D Hammoudi, CA Moubareck, N Hakime, M Houmani… - International Journal of Infectious Diseases, 2015