作者
Erna S Arnardottir, Greg Maislin, Richard J Schwab, Bethany Staley, Bryndis Benediktsdottir, Isleifur Olafsson, Sigurdur Juliusson, Micah Romer, Thorarinn Gislason, Allan I Pack
发表日期
2012/7/1
期刊
Sleep
卷号
35
期号
7
页码范围
921-932
出版商
Oxford University Press
简介
Study Objectives
To assess the relative roles and interaction of obstructive sleep apnea (OSA) severity and obesity on interleukin-6 (IL-6) and C-reactive protein (CRP) levels.
Design
Cross-sectional cohort.
Setting
The Icelandic Sleep Apnea Cohort.
Participants
454 untreated OSA patients (380 males and 74 females), mean ± standard deviation age 54.4 ± 10.6 yr.
Interventions
N/A.
Measurements and Results
Participants underwent a sleep study, abdominal magnetic resonance imaging to measure total abdominal and visceral fat volume, and had fasting morning IL-6 and CRP levels measured in serum. A significantly higher correlation was found for BMI than visceral fat volume with CRP and IL-6 levels. Oxygen desaturation index, hypoxia time, and minimum oxygen saturation (SaO2 …
学术搜索中的文章
ES Arnardottir, G Maislin, RJ Schwab, B Staley… - Sleep, 2012