作者
Giulia Scioscia, Isabel Blanco, Ebymar Arismendi, Felip Burgos, Concepción Gistau, Maria Pia Foschino Barbaro, Bartolome Celli, Denis E O'Donnell, Alvar Agustí
发表日期
2017/2/1
期刊
Thorax
卷号
72
期号
2
页码范围
117-121
出版商
BMJ Publishing Group Ltd
简介
Background
Some patients with COPD report frequent acute exacerbations (AECOPD) of the disease (FE), whereas others suffer them infrequently (IE). Because the current diagnosis of exacerbation relies on patient's perception of increased symptoms (mostly dyspnoea), we hypothesised that dyspnoea perception might be different in COPD patients with FE (≥2 exacerbations or 1 hospitalisation due to AECOPD in the previous year) or IE (≤1 exacerbation in the previous year), AECOPD being defined by the institution antibiotics and/or steroids treatment, or hospital admission.
Objective
To test the hypothesis that dyspnoea perception is increased in FE and/or decreased in IE with COPD.
Methods
We compared the perception of dyspnoea (Borg scale), mouth occlusion pressure 0.1 s after the onset of inspiration (P0.1) and ventilatory response to hypercapnia (ΔVE/ΔPETCO2) in 34 clinically stable COPD patients …
学术搜索中的文章
G Scioscia, I Blanco, E Arismendi, F Burgos, C Gistau… - Thorax, 2017