作者
Alan N Barkun, Myriam Martel, Youssef Toubouti, Elham Rahme, Marc Bardou
发表日期
2009/4/1
来源
Gastrointestinal endoscopy
卷号
69
期号
4
页码范围
786-799
出版商
Mosby
简介
BACKGROUND AND OBJECTIVE
Optimal endoscopic hemostasis remains undetermined. This was a systematic review of contemporary methods of endoscopic hemostasis for patients with bleeding ulcers that exhibited high-risk stigmata.
SETTING
Randomized trials that evaluated injection, thermocoagulation, clips, or combinations of these were evaluated from MEDLINE, EMBASE, and CENTRAL (1990-2006).
PATIENTS
A total of 4261 patients were evaluated.
OUTCOMES
Outcomes were rebleeding (primary), surgery, and mortality (secondary). Summary statistics were determined; publication bias and heterogeneity were sought by using funnel plots or by subgroup analyses and meta-regression.
RESULTS
Forty-one trials assessed 4261 patients. All endoscopic therapies decreased rebleeding versus pharmacotherapy alone, including sole intravenous (IV) proton pump inhibition (PPI) (OR 0.56 [95% CI, 0.34 …
引用总数
学术搜索中的文章
AN Barkun, M Martel, Y Toubouti, E Rahme, M Bardou - Gastrointestinal endoscopy, 2009