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Particle dispersion can be influenced by human activities' inducing effect, which may not be allowed in high-demanded cleanness environment, such as operation room. The application of dynamic mesh simulation method has been widely applied for objects moving, which is not CPU-friendly in calculation as well as complex meshing required. Thus, we proposed a new method of momentum theory to investigate human motion induced effects on indoor environments (i.e., momentum source implemented into Navier-Stokes equations to simulate human/objects moving). Experiments were conducted for validation. RNG k-ε model was adopted for turbulence modeling. Both methods of dynamic mesh and momentum theory were used to investigate the impacts of human induced motion on indoor environments of airflow distributions and particles dispersion. It was found that momentum theory method is sufficiently fine …